Nobel Prize in Medicine 2026 awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel for discovery concerning optogenetics

The 2026 Nobel Prize in Physiology or Medicine has been jointly awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel by the Nobel Assembly at the Karolinska Institute on 5 October 2026 in Stockholm, Sweden for their discoveries concerning light-gated ion channels and optogenetics. Check the complete details about the Nobel Prize in Medicine 2026 winners with prize money of $1.2 million and some key facts and important details about the Medicine Physiology Nobel Prize here in this Veranda RACE article.

Nobel Prize in Medicine 2026 Winners Announced

The Nobel Prize in Physiology or Medicine 2026 has been jointly awarded to “Karl Deisseroth, Peter Hegemann and Georg Nagel” by the Nobel Academy at the Karolinska Institute for “for their discoveries concerning light-gated ion channels and optogenetics’ in Stockholm, Sweden on 5 October 2026.

Nobel Prize in Medicine 2026 awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel for discovery concerning optogenetics

This year’s Nobel Medicine Prize recipients in 2026 are Karl Deisseroth from USA, Peter Hegemann from the Germany and Georg Nagel from Germany.

Their work has helped scientists across the world understand how light can be used to control the activity of cells, particularly nerve cells. This has opened new possibilities for studying the brain and developing treatments for neurological and other disorders.

Who are the Nobel Prize Medicine Winners in 2026?

The Nobel Assembly at the Karolinska Institute in Sweden has awarded the 2026 Nobel Prize for Physiology or Medicine jointly to Karl Deisseroth, Peter Hegemann and Georg Nagel for ‘their discoveries concerning light-gated ion channels and optogenetics’.

The Nobel Prize Medicine laureates are selected by the Nobel Assembly of Sweden’s Karolinska Institute medical university. The Nobel Prize Medicine Winners 2026 will receive a prize sum of 12 million Swedish crowns or $1.2 million, which is shared if there are multiple winners.

Nobel Prize in Medicine 2026 awarded to Karl Deisseroth, Peter Hegemann and Georg Nagel for discovery concerning optogenetics

Karl Deisseroth

Born: 18 November 1971

Born in: Boston, USA

Working in: Standford University, USA Howard Hughes Medical Institute USA

Prize Share: 1/3

Peter Hegemann

Born: 11 December 1954

Born in: Munster, Germany

Working in: Humboldt University of Berlin, Germany

Prize Share: 1/3

Georg Nagel

Born: 24 August 1953

Born in: Weingarten, Germany

Working in: University of Wurzburg, Germany

Prize Share: 1/3

Peter Hegemann and Georg Nagel discovered channel rhodopsin, a protein with unique properties. They found that regardless of which cell they put the protein in, those cells became light sensitive.

Karl Deisseroth introduced the gene for channelrhodopsin into the nerve cells from rats. By illuminating the cells with blue light, Deisseroth was able to trigger a nerve signal. Later, Peter made the light-controlled switch for nerve cells to work in the brains of living mice.

This method of controlling nerve signals with light is now called optogenetics.

Using optogenetics, researchers have been able to revel neural circuits governing specific memories, feelings and behaviours relevant for neurological and psychiatric disorders.

What is the Nobel Prize in Physiology or Medicine?

The Nobel Prize in Physiology or Medicine is an international prize.

It is an award given in the field of medicine or physiology and administered by the Nobel Assembly at the Karolinska University ins Stockholm, Sweden.

The Nobel Prize in Medicine is awarded to outstanding discoveries in the field of medicine or physiology.

This Nobel Prize for Physiology or Medicine was established in 1901 by the Nobel Foundation according to Alfred Nobel’s will to create a series of prizes for those who confer the ‘greatest benefit on Mankind’ in Physics, Chemistry, Peace, Physiology or Medicine and Literature.

The laureates of the Nobel Prize in Medicine or Physiology are selected by the Nobel Assembly at the Karolinska Institute in Sweden.

The Norwegian Nobel Foundation usually announces the winners of the Nobel Prize in Medicine or Physiology in the month of October every year.

The cash reward for the Nobel Prize for Medicine or Physiology in 2026 will be 12 million Swedish kroner (SEK) or $1.2 million.

Key Facts about the Nobel Prize in Medicine

The Nobel Prize in Physiology or Medicine has been awarded 117 times since 1901 until 2026.

Between 1901 and 2026, the Nobel Prize in Economic Sciences has been awarded to 235 individual Nobel Peace medicine Laureates.

The Nobel Prize in Physiology or Medicine was first awarded in 1901 to German physiologist Emil von Behring ‘for his work on serum therapy and the development of vaccine against diptheria’.

Frederick Banting is the youngest Nobel Medicine Prize laureate and was awarded in 1923 at the age of 31 ‘for the discovery of insulin’.

The oldest Nobel Medicine Prize laureate is Peyton Rous and he was received it at the age of 87 in 1996 ‘for his discovery of tumour-inducing viruses.

Gerty Cori was the first woman laureate to be awarded the Nobel Prize in Medicine in 1947 ‘for her role in elucidating the metabolism of glucose, including treatment of diabetes’.

Out of the 235 Nobel Medicine Prize laureates, 14 are women. Of these 14 women, Barabara McClintock is the only one who has received an unshared Nobel Prize in Medicine.

The Nobel Prize in Physiology or Medicine 2025 was jointly awarded to Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi ‘for their discoveries concerning peripheral immune tolerance and regulatory T cells’.

Nobel Prize Medicine Winners from 1901 to 2026

You can find the list of Nobel Prize Winners for Medicine or Physiology starting from 1901 until 2026 in the below table from Veranda RACE:

Nobel Prize Medicine Winners: 1091 to 2026

Winners

Year

Citation

Emil von Behring

1901

Serum therapy, particularly against diphtheria.

Ronald Ross

1902

Explaining how malaria enters the body.

Niels Ryberg Finsen

1903

Treating diseases, especially lupus vulgaris, with concentrated light.

Ivan Pavlov

1904

Explaining the physiology of digestion.

Robert Koch

1905

Research and discoveries concerning tuberculosis.

Camillo Golgi; Santiago Ramón y Cajal

1906

Revealing the nervous system’s structure.

Alphonse Laveran

1907

Establishing the disease-causing role of protozoa.

Ilya Mechnikov; Paul Ehrlich

1908

Research on immunity.

Theodor Kocher

1909

Research on thyroid function, disease and surgery.

Albrecht Kossel

1910

Research on proteins and nucleic substances in cells.

Allvar Gullstrand

1911

Explaining the eye’s optical properties.

Alexis Carrel

1912

Vascular suturing and transplantation of vessels and organs.

Charles Richet

1913

Research on anaphylaxis.

Robert Bárány

1914

Research on the vestibular apparatus’s function and disorders.

—

1915

Prize not awarded.

—

1916

Prize not awarded.

—

1917

Prize not awarded.

—

1918

Prize not awarded.

Jules Bordet

1919

Discoveries about immunity.

August Krogh

1920

Discovering how capillary activity is regulated.

—

1921

Prize not awarded.

Archibald V. Hill

1922

Explaining heat production in muscles.

Otto Meyerhof

1922

Linking oxygen consumption and lactic acid metabolism in muscles.

Frederick G. Banting; John Macleod

1923

Discovering insulin.

Willem Einthoven

1924

Explaining the electrocardiogram’s mechanism.

—

1925

Prize not awarded.

Johannes Fibiger

1926

Work recognised as the discovery of Spiroptera carcinoma.

Julius Wagner-Jauregg

1927

Using malaria inoculation to treat dementia paralytica.

Charles Nicolle

1928

Research on typhus.

Christiaan Eijkman

1929

Discovering the vitamin that prevents polyneuritis.

Sir Frederick Hopkins

1929

Discovering vitamins essential for growth.

Karl Landsteiner

1930

Identifying human blood groups.

Otto Warburg

1931

Explaining the respiratory enzyme’s nature and action.

Sir Charles Sherrington; Edgar Adrian

1932

Discoveries about neuron function.

Thomas H. Morgan

1933

Establishing chromosomes’ role in inheritance.

George H. Whipple; George R. Minot; William P. Murphy

1934

Developing liver treatment for anaemia.

Hans Spemann

1935

Discovering the organiser effect in embryo development.

Sir Henry Dale; Otto Loewi

1936

Establishing chemical transmission of nerve signals.

Albert Szent-Györgyi

1937

Discoveries about biological oxidation, vitamin C and fumaric acid.

Corneille Heymans

1938

Explaining sinus and aortic mechanisms regulating breathing.

Gerhard Domagk

1939

Discovering Prontosil’s antibacterial action.

—

1940

Prize not awarded.

—

1941

Prize not awarded.

—

1942

Prize not awarded.

Henrik Dam

1943

Discovering vitamin K.

Edward A. Doisy

1943

Identifying vitamin K’s chemical nature.

Joseph Erlanger; Herbert S. Gasser

1944

Revealing specialised functions of individual nerve fibres.

Sir Alexander Fleming; Ernst B. Chain; Sir Howard Florey

1945

Discovering penicillin and its effectiveness against infections.

Hermann J. Muller

1946

Demonstrating that X-rays cause mutations.

Carl Cori; Gerty Cori

1947

Explaining glycogen’s catalytic conversion.

Bernardo Houssay

1947

Establishing anterior pituitary hormone involvement in sugar metabolism.

Paul Müller

1948

Discovering DDT’s effectiveness against arthropods.

Walter Hess

1949

Explaining how the interbrain coordinates internal organs.

Egas Moniz

1949

Work recognised for leucotomy’s therapeutic value in certain psychoses.

Edward C. Kendall; Tadeus Reichstein; Philip S. Hench

1950

Discovering adrenal cortex hormones, their structures and effects.

Max Theiler

1951

Discoveries about yellow fever and its control.

Selman A. Waksman

1952

Discovering streptomycin, effective against tuberculosis.

Hans Krebs

1953

Discovering the citric acid cycle.

Fritz Lipmann

1953

Discovering coenzyme A and its metabolic importance.

John F. Enders; Thomas H. Weller; Frederick C. Robbins

1954

Growing poliovirus in cultures of different tissues.

Hugo Theorell

1955

Explaining oxidation enzymes’ nature and action.

André F. Cournand; Werner Forssmann; Dickinson W. Richards

1956

Discoveries involving cardiac catheterisation and circulatory disorders.

Daniel Bovet

1957

Discovering synthetic compounds that block certain bodily substances.

George Beadle; Edward Tatum

1958

Showing how genes regulate specific chemical processes.

Joshua Lederberg

1958

Discovering bacterial genetic recombination and genetic organisation.

Severo Ochoa; Arthur Kornberg

1959

Explaining how RNA and DNA are synthesised.

Sir Frank Macfarlane Burnet; Peter Medawar

1960

Discovering acquired immune tolerance.

Georg von Békésy

1961

Explaining physical stimulation mechanisms in the cochlea.

Francis Crick; James Watson; Maurice Wilkins

1962

Revealing nucleic acid structure and its role in information transfer.

Sir John Eccles; Alan Hodgkin; Andrew Huxley

1963

Explaining ionic mechanisms of nerve-cell excitation and inhibition.

Konrad Bloch; Feodor Lynen

1964

Explaining cholesterol and fatty acid metabolism and regulation.

François Jacob; André Lwoff; Jacques Monod

1965

Explaining genetic regulation of enzyme and virus production.

Peyton Rous

1966

Discovering viruses that cause tumours.

Charles B. Huggins

1966

Discovering hormonal treatment for prostate cancer.

Ragnar Granit; Keffer Hartline; George Wald

1967

Explaining physiological and chemical processes underlying vision.

Robert W. Holley; H. Gobind Khorana; Marshall W. Nirenberg

1968

Deciphering the genetic code’s role in making proteins.

Max Delbrück; Alfred D. Hershey; Salvador E. Luria

1969

Explaining viral replication and genetic structure.

Sir Bernard Katz; Ulf von Euler; Julius Axelrod

1970

Explaining neurotransmitter storage, release and inactivation.

Earl W. Sutherland, Jr.

1971

Explaining how hormones act.

Gerald M. Edelman; Rodney R. Porter

1972

Revealing antibodies’ chemical structure.

Karl von Frisch; Konrad Lorenz; Nikolaas Tinbergen

1973

Explaining the organisation and triggering of individual and social behaviour.

Albert Claude; Christian de Duve; George E. Palade

1974

Revealing cells’ structural and functional organisation.

David Baltimore; Renato Dulbecco; Howard M. Temin

1975

Explaining interactions between tumour viruses and cellular genetic material.

Baruch S. Blumberg; D. Carleton Gajdusek

1976

Discovering mechanisms behind infectious diseases’ origins and spread.

Roger Guillemin; Andrew V. Schally

1977

Discovering how the brain produces peptide hormones.

Rosalyn Yalow

1977

Developing radioimmunoassays for peptide hormones.

Werner Arber; Daniel Nathans; Hamilton O. Smith

1978

Discovering restriction enzymes and their genetic applications.

Allan M. Cormack; Godfrey N. Hounsfield

1979

Developing computed tomography (CT).

Baruj Benacerraf; Jean Dausset; George D. Snell

1980

Discovering genetically determined cell-surface structures controlling immune responses.

Roger W. Sperry

1981

Revealing specialised functions of the brain’s hemispheres.

David H. Hubel; Torsten N. Wiesel

1981

Explaining how the visual system processes information.

Sune K. Bergström; Bengt I. Samuelsson; John R. Vane

1982

Discoveries about prostaglandins and related active substances.

Barbara McClintock

1983

Discovering movable genetic elements.

Niels K. Jerne; Georges J.F. Köhler; César Milstein

1984

Theories of immune-system control and principles for producing monoclonal antibodies.

Michael S. Brown; Joseph L. Goldstein

1985

Explaining how cholesterol metabolism is regulated.

Stanley Cohen; Rita Levi-Montalcini

1986

Discovering growth factors.

Susumu Tonegawa

1987

Explaining the genetic basis of antibody diversity.

Sir James W. Black; Gertrude B. Elion; George H. Hitchings

1988

Establishing key principles of drug treatment.

J. Michael Bishop; Harold E. Varmus

1989

Establishing the cellular origin of retroviral cancer genes.

Joseph E. Murray; E. Donnall Thomas

1990

Discoveries enabling organ and cell transplantation to treat disease.

Erwin Neher; Bert Sakmann

1991

Revealing how individual cellular ion channels function.

Edmond H. Fischer; Edwin G. Krebs

1992

Explaining reversible protein phosphorylation in biological regulation.

Richard J. Roberts; Phillip A. Sharp

1993

Discovering split genes.

Alfred G. Gilman; Martin Rodbell

1994

Discovering G-proteins and their cellular signalling role.

Edward B. Lewis; Christiane Nüsslein-Volhard; Eric F. Wieschaus

1995

Explaining genetic regulation of early embryo development.

Peter C. Doherty; Rolf M. Zinkernagel

1996

Explaining the specificity of cell-mediated immunity.

Stanley B. Prusiner

1997

Discovering prions as a new infectious principle.

Robert F. Furchgott; Louis J. Ignarro; Ferid Murad

1998

Establishing nitric oxide’s signalling role in the cardiovascular system.

Günter Blobel

1999

Discovering signals directing proteins to their cellular destinations.

Arvid Carlsson; Paul Greengard; Eric Kandel

2000

Discoveries about signalling within the nervous system.

Leland Hartwell; Tim Hunt; Sir Paul Nurse

2001

Identifying central regulators of cell division.

Sydney Brenner; H. Robert Horvitz; John E. Sulston

2002

Explaining genetic control of organ formation and programmed cell death.

Paul C. Lauterbur; Sir Peter Mansfield

2003

Discoveries enabling magnetic resonance imaging (MRI).

Richard Axel; Linda B. Buck

2004

Discovering smell receptors and the organisation of smell perception.

Barry J. Marshall; J. Robin Warren

2005

Discovering Helicobacter pylori and its role in gastritis and ulcers.

Andrew Z. Fire; Craig C. Mello

2006

Discovering gene silencing through double-stranded RNA.

Mario R. Capecchi; Sir Martin J. Evans; Oliver Smithies

2007

Establishing targeted gene modification in mice using embryonic stem cells.

Harald zur Hausen

2008

Establishing that human papillomaviruses cause cervical cancer.

Françoise Barré-Sinoussi; Luc Montagnier

2008

Discovering HIV.

Elizabeth H. Blackburn; Carol W. Greider; Jack W. Szostak

2009

Explaining chromosome protection by telomeres and telomerase.

Robert G. Edwards

2010

Developing in vitro fertilisation (IVF).

Bruce A. Beutler; Jules A. Hoffmann

2011

Discovering how innate immunity is activated.

Ralph M. Steinman

2011

Discovering dendritic cells and their adaptive-immunity role.

Sir John B. Gurdon; Shinya Yamanaka

2012

Showing that mature cells can be reprogrammed into pluripotent cells.

James E. Rothman; Randy W. Schekman; Thomas C. Südhof

2013

Discovering how vesicle transport is controlled inside cells.

John O’Keefe; May-Britt Moser; Edvard I. Moser

2014

Discovering the brain’s positioning-system cells.

William C. Campbell; Satoshi Ōmura

2015

Discovering a new treatment for roundworm infections.

Tu Youyou

2015

Discovering a new malaria treatment.

Yoshinori Ohsumi

2016

Explaining mechanisms of autophagy.

Jeffrey C. Hall; Michael Rosbash; Michael W. Young

2017

Explaining molecular control of the circadian clock.

James P. Allison; Tasuku Honjo

2018

Discovering cancer treatment by releasing immune-system inhibition.

William G. Kaelin Jr; Sir Peter J. Ratcliffe; Gregg L. Semenza

2019

Explaining how cells detect and adapt to oxygen levels.

Harvey J. Alter; Michael Houghton; Charles M. Rice

2020

Discovering the hepatitis C virus.

David Julius; Ardem Patapoutian

2021

Identifying receptors that detect temperature and touch.

Svante Pääbo

2022

Discoveries about extinct hominin genomes and human evolution.

Katalin Karikó; Drew Weissman

2023

Discovering nucleoside modifications enabling effective COVID-19 mRNA vaccines.

Victor Ambros; Gary Ruvkun

2024

Discovering microRNA and its control of gene activity after transcription.

Mary E. Brunkow; Fred Ramsdell; Shimon Sakaguchi

2025

Discoveries explaining peripheral immune tolerance.

Kar Deisseroth, Peter Hegemann, Georg Nagel

2026

Discoveries concerning light-gated ion channels and optogenetics.

Nobel Prize Winners in 2025

Find the detailed list of other Nobel Prize winners in 2025 and laureates with this table below:

Nobel Prize Winners List in 2025

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FAQs

Yes. The winners of the Nobel Medicine Prize for 2026 were announced on 5 October 2026 by the Nobel Academy at the Karolinska Institute in Stockholm, Sweden.
The Nobel Prize in Physiology or Medicine 2026 has been jointly awarded to “Karl Deisseroth, Peter Hegemann and Georg Nagel” by the Nobel Academy at the Karolinska Institute for “for their discoveries concerning light-gated ion channels and optogenetics’ in Stockholm, Sweden on 5 October 2026.

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